Sebaka sa Spike glycoprotein receptor-binding (RBD) sa SARS-CoV-2 se hokahanya setlamo sa kokoana-hloko ho li-angiotensin-converting enzyme 2 (ACE2) receptor holim'a lisele tsa motho.Ka hona, tšebelisano ea Spike-ACE2 ke ntlha ea bohlokoa e khethollang ts'oaetso ea vaerase.Sehlopha se secha sa phylogenetic sa SARS-CoV-2 (leloko la B.1.1.7), se nang le sebaka sa amino acid ho Spike RBD (N501Y mutation).
Ho latela lipatlisiso tse ncha tse tsoang Lefapheng la Bophelo la UK, tse ipapisitseng le tlhaiso-leseling ea tatellano ea liphatsa tsa lefutso, lefu la seoa le mohlala, ts'oaetso ea mefuta e fapaneng ea SARS-CoV-2 e batla e phahame ka 40-70% ho feta bo-ramahlale ba bang ba ntlafatso ba fumanehang. .Karabelo e potlakileng le ho lemoha ke e 'ngoe ea mehato ea bohlokoa ea thibelo le taolo.
Kit e sebelisetsoa in vitro qualitative ho lemoha mefuta ea ORF1ab/N/S ea novel coronavirus 2019-nCoV mefuteng ea phefumoloho, le ho etsa typing ea phetoho ho N501Y ka nako e le 'ngoe.
Sesebelisoa se sebelisa mokhoa oa ARMS, se nka mofuta oa S oa novel coronavirus (2019-nCoV) joalo ka sebaka seo ho shebiloeng ho thaepa ka sona, se rala li-primers le li-probes tse khethehileng tsa N501Y.
| Lihlahisoa | Lintlha | Mocheso oa polokelo | Tlhaloso |
| Nako ea 'Nete ea PCR Kit ea NovelCoronavirus 2019-nCoV leNovel Coronavirus 2019-nCoVPhetoho ea Lefu (N501Y) | 48T | -20 ℃ | Bahlahlobisisi: Mofuta oa hlaha oa N501Y,Mofuta oa Mutant oa N501Y, ORF1ab,N gene le Taolo ea ka hare |
Template e lumellana
- Litlhapi tsa Oropharyngeal
- Nasopharyngeal Swab
- Mokelikeli oa Bronchoalveolar Lavage
- Sekhohlela
Likarolo tsa Kit
- Tšireletso ea karabelo ea RT-PCR
- Motsoako oa enzyme ea RT-PCR
- Taolo e ntle ea mofuta o hlaha
- Taolo e ntle e fetotsoeng
- Taolo e mpe
Mofuta oa phetoho ea N501Y
