Letsatsi la Lefatše la Arthritis ke ketsahalo ea lefats'e ea tlhokomeliso ea bophelo bo botle e hlophisitsoeng selemo se seng le se seng ka la 12 Mphalane ho lemosa batho ka mafu a ramatiki le mesifa, phello ea ona bophelong ba motho le ho ruta batho matšoao le mehato ea thibelo le tataiso bakeng sa tlhahlobo ea kapele ho sebetsana le mathata a mang. .
Bohlokoa ba Letsatsi la Lefatše la Ramatiki (WAD)
Ramatiki ke lefu la ho ruruha la manonyeletso, le amang manonyeletso a mahlahahlaha a pota-potileng lenonyeletso, le lisele tse ling tse kopanyang, tse bakang bohloko ba manonyeletso le ho satalla.Ho na le mefuta e fetang 100 ea ramatiki, empa e atileng haholo ke ramatiki ea masapo le ramatiki.Ka lebaka la ho hloka tlhokomeliso le tšehetso, ramatiki le boemo bo amanang le eona li holofalitse bophelo bo bongata lefatšeng ka bophara.Ha ho na phekolo e khethehileng bakeng sa ramatiki, khetho ea phekolo e fapana ho latela mefuta, kahoo ho bohlokoa ho utloisisa letšoao le matšoao le ho fumana tlhahlobo ea pele ho fumana phekolo e nepahetseng.
Mofuta o Tloaelehileng ka ho Fetisisa oa Ramatiki
Mefuta e tloaelehileng haholo e kenyelletsa lefu la masapo a manonyeletso (OA), ramatiki ea lefuba (RA), ramatiki ea psoriatic (PsA), fibromyalgia le gout.Ramatiki le mafu a amanang le tsona a ka baka bohloko bo fokolisang, bo fetolang bophelo ka litsela tse fapaneng.
Ramatiki ea ramatiki (RA) ke e 'ngoe ea mafu a tloaelehileng a ho ruruha a manonyeletso, a atileng haholo ho basali ba lilemong tse bohareng.Haholo-holo e bonahatsoa e le e sa foleng, symmetrical, progressive polyarthritis.Ntle le ho ama manonyeletso, ho na le liponahatso tse ngata tse eketsehileng, tse kang letlalo, mahlo, pelo, matšoafo, tsamaiso ea mali, joalo-joalo.
Ho ata ha RA ke 0.5-1%, 'me karo-karolelano ea mosali ho monna ke 3:1.E phahame ka makhetlo a 4 ho isa ho a 5 ho basali ba ka tlase ho lilemo tse 50, empa ka mor'a lilemo tse 60 karo-karolelano e ba hoo e ka bang 2 ho 1.Batho ba nang le lefu la ramatiki hangata ba na le boemo bo phahameng ba protheine ea C-reactive (CRP), e ka 'nang ea bontša boteng ba mokhoa oa ho ruruha' meleng.Liteko tse ling tse tloaelehileng tsa mali li sheba li-antibodies tsa rheumatoid factor (RF) le anti-cyclic citrullinated peptide (anti-CCP).
RA(Ramatiki ea ramatiki)
Ramatiki ea Ramatiki ke boloetse bo sa foleng ba ho ruruha bo ka amang ho feta manonyeletso a hau feela.Ho batho ba bang, boemo bona bo ka senya mekhoa e mengata e fapaneng ea 'mele, ho kenyelletsa letlalo, mahlo, matšoafo, pelo le methapo ea mali.
Boloetse ba autoimmune, ramatiki ea ramatiki e etsahala ha sesole sa hau sa 'mele se hlasela lisele tsa' mele oa hau ka phoso.
Ho fapana le tšenyo e bakoang ke lefu la masapo a manonyeletso, ramatiki ea ramatiki e ama lera la manonyeletso, e baka ho ruruha ho bohloko hoo qetellong ho ka fellang ka ho khoholeha ha masapo le ho holofala ha manonyeletso.
Anti-CCP Anti-Cyclic Citrullinated Peptide Antibody
Anti-cyclic citrullinated peptide antibody (Anti-CCP): Ke sekhechana sa polypeptide sa protheine ea cyclic polyguanidine 'me haholo-holo ke lesole la 'mele la mofuta oa IgG.Li-anti-cyclic citrullinated peptide antibodies li hlahisoa ka boithatelo ke li-lymphocyte tsa B tsa bakuli ba nang le ramatiki ea ramatiki (RA), ha li-lymphocyte tsa B tsa bakuli ba nang le mafu a mang le batho ba tloaelehileng li sa hlahise li-anti-cyclic citrullinated peptide antibodies.Ka hona, e na le kutlo e phahameng le e ikhethang bakeng sa ramatiki ea ramatiki, 'me ke sesupo se ikhethileng bakeng sa tlhahlobo ea pele ea ramatiki ea ramatiki.
Anti-CCP (Anti-cyclic citrullinated peptides) ke mofuta oa li-autoantibody: lesole la 'mele le sebetsang khahlanong le li-antibodies tse tloaelehileng tsa 'mele oa hau.Anti-CCP e atisa ho hlahisoa ha u e-na le ramatiki ea ramatiki.Li-autoantibodies tsena li qala ho shebana le ho hlasela lisele tse ling tse phetseng hantle.
Lipontšo tsa pele tsa tlhahlobo ea ramatiki ea ramatiki: li-anti-cyclic citrullinated antibodies li hlaha lilemo tse 1-10 pele ho lipontšo tsa kliniki tsa ramatiki ea ramatiki, e loketseng tlhahlobo ea 'mele ea batho ba phetseng hantle le tlhahlobo ea pele ea lihlopha tse kotsing e kholo.Hajoale,ho lumeloa hore kutloisiso ea li-anti-cyclic citrullinated peptide antibodies bakeng sa ho hlahlojoa ha ramatiki ea ramatiki ke 50% ho 78%, e khethehileng ke 96%, 'me tekanyo e ntle ea bakuli ba pele e ka fihla ho 80%.
AehebopheloAnti-CCP Ptsela
Aehealth Anti-CCP (Anti-cyclic Citrullinated Peptide Antibody) Tlhahlobo e potlakileng ea Teko e amohela mokhoa oa Immunofluorescence Assay.
The Anti-CCP kit ea ho lemoha linear range ke 10～500 U/mL;coefficient ea ho hokahanya ha linear pakeng tsa mahloriso a theoretical le mahloriso a lekantsoeng a ka fihla r≥0.990.E sebelisoa le tlhahlobo ea Aehealth Lamuno X immunofluorescence ho felehetsa tlhahlobo ea pele le tlhahlobo ea kalafo ea bakuli ba rheumatism.
Li-antibodies tsa anti-CCP li hokahana le likarolo tsa ts'ebetso ea RA.
Li-anti-CCP li bolela esale pele tšenyo ea RA.
Nako ea poso: Oct-12-2022